- 14C Urea Breath Test Kit
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- Model NO.: 14C-Urea Test Kit
- 14c-Urea Capsule: 27.8kbq/Grain
- Specification: GMP
- HS Code: 9027
- Collection Card: 40 PCS/Package
- Trademark: Headway
- Origin: China
Helicobacter pylori (H. pylori) is the primary cause of gastritis and peptic ulcer disease and has been linked to the onset of gastric cancer in some individuals. The need for a simple, non-invasive and accurate diagnostic technology for the detection of H. Pylori infection was met by the development of urea breath test, which allows infection status to be evaluated without the need for costly and invasive endoscopies.
The principle of 14C-Urea Breath Test
The 14C-Urea Breath Test (UBT) is based on the detection of the enzyme urease, produced by Helicobacter pylori. Since urease is not present in normal human tissues, and since other urease-producing bacteria do not colonize the stomach, the presence of urease in the stomach can be equated with Helicobacter pylori infection.
In the presence of urease, orally administered 14C urea will be hydrolyzed into ammonia and 14CO2.14CO2 is absorbed into the blood circulation and exhaled by the lung. The presence of a significant amount of 14CO2 in the exhaled breath indicates active Helicobacter pylori infection.
The 14C-Urea Breath Test offers a range of advantages as below:
Sensitivity 95%, specificity 95%-100%.
Non-invasive, no endoscopic tube insertion, well tolerated by patients.
Near-patient testing, analysis made on site, minimal inconvenience for patients.
Easy operation, no special handling required.
The entire test is finished in 30 minutes, test result available on site.
The operation procedure of 14C-Urea Breath Test can be finished by four steps:
1. 14C-Urea capsule: 27.8kBq(0.75μCi)/grain * 40 grains / package
2. Collection card: 40 pcs/package